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Any disruption in the mechanism can have great impact on overall metabolic activities. Once the metabolism is disturbed, it has been found to cause a series of abnormalities, one major factor being hair loss. Hypothyroidism has often been seen in women. It is often characterized by problems such as lethargy, menstrual imbalance and deceleration of metabolic rate. All of these factors contribute to hair loss. On the other hand, highly excessive functional activities of the thyroid gland can also cause hair loss. Hormonal dysfunction within the body has a massive effect on hair loss. Hair loss occurs when dihydrotestosterone (DHT) shrinks the hair follicles and eventually causes them to disappear completely. The problem of hypothyroidism and hyperthyroidism both encourage the conversion process of testosterone into DHT which accelerates hair loss in both men and women of all ages.But most of the reasons points on the fact that it is the biological cycle that usually determines the production of melanin in our body. Getting a gray hair or even white hair is a process that is associated with the aging of our body. Most of the people start getting gray hair at an age of 50 but it may also begin as early as 20 for some individuals. Most of the people may not be aware of the fact that hair transplant is safe for aged patients or not We also know that age alone may not stop a person from undergoing hair transplant. A number of physicians have also reported few cases in which they have completed hair transplant successfully even at the age of 80. Moreover hair loss is very common at the age of 80, so hair transplant has to be done at this age. Considering aged patients for hair transplant should in fact be one of the preferred priorities.