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Out of all the medications, Propecia/Finasteride has proved to be the most effective hair loss treatment for men. Propecia/Finasteride works on hair loss at the vertex of your crown and the anterior mid-scalp area, the two areas of your head most affected by hair loss. Propecia/Finasteride is synthetic 4-azasteroid compound drug, which is a specific inhibitor of steroid Type II 5α-reductase, an intracellular enzyme that converts the androgen testosterone into 5α-dihydrotestosterone (DHT).It acts on telogen phase and helps to regenerate hair and henceforth reduce the loss of hair. The drug's active ingredient, finasteride, is already approved for the treatment of prostate enlargement. It works by blocking an enzyme called 5-alpha reductase, which primary is responsible for the formation of dihydro-testosterone in an average male. The enzyme converts testosterone into DHT, and hence it is believed that DHT is a key factor in male pattern hair loss. Propecia/Finasteride decreases the concentration of DHT in a man's scalp by about two-thirds.Both Iamin and Tricomin were invented and subsequently patented by Dr. Loren Pickart. As I stated in the 1997 article about these compounds, "These drugs are copper based compounds that have certain peptides added to them. When put on the skin they have profound anti inflammatory properties and increase the rate at which skin heals dramatically (hence Iamin700s approval for wound healing). As I mentioned earlier, chronic inflammation at the site of the hair follicle appears to be a major link in the chain of what makes hair fall out." 2005 thoughts: Unfortunately these products did not turn out to be nearly as effective for MPB as I had hoped. Feedback was lackluster at best. I believe they still have some use in multi ingredient formulas that may add some small additional benefit, but the general advice is they are minimally effective for MPB alone. Nizoral Shampoo 1997: "Nizoral is an anti fungal shampoo and the active ingredient is a plant derivative called Ketoconazol and is produced by Janssen Pharmaceuticals. How and why Nizoral works on hair loss in not very well understood.